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May 5, 2006
9780801888908
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6.00 Inches (US)
$57.00 USD, £42.00 GBP
v2.1 Reference

The Effects of Estrogen on Brain Function

This timely volume reviews current data on the effects of estrogen on the central nervous system, highlighting clinical aspects of this topic. Experts from the fields of psychiatry, pharmacology, neurology, and geriatrics collaborate to clarify the known risks and benefits of hormone therapy and explore questions that remain to be elucidated.

Among the topics discussed:
" Preclinical data on estrogen's effects on cognitive performance
" The short-lived effects of hormone replacement therapy on cognitive function
" Structural and functional brain imaging data regarding
estrogen's effects on the central nervous system
" Preclinical efforts to develop effective NeuroSERMs for the brain
" The effects of estrogen on mood


Citing the ongoing confusion over the risks and benefits of estrogen therapy, the contributors emphasize the need for additional research on medication, doses, preparations, methods of administration, alternative therapies, and supplements.

This volume educates researchers, clinicians, and students on the current knowledge—including the effects of estrogen on mood, cognition, and brain metabolism—and provides guidelines for clinical practice and future research.

Contributors: Roberta Diaz Brinton, Ph.D., University of Southern California; Cheri L. Geist, B.A., David Geffen School of Medicine, University of California at Los Angeles; Robert B. Gibbs, Ph.D., University of Pittsburgh School of Pharmacy; Eva Hogervorst, Ph.D., University of Loughborough and University of Oxford; Pauline M. Maki, Ph.D., Neuropsychiatric Institute, University of Illinois–Chicago; Peter J. Schmidt, M.D., National Institute of Mental Health; Daniel H. S. Silverman, M.D., Ph.D., David Geffen School of Medicine, University of California at Los Angeles; Katherine E. Williams, M.D., Stanford University School of Medicine; Kristine Yaffe, M.D., University of California, San Francisco, and San Francisco VA Medical Center; Laurel N. Zappert, B.A., Stanford University School of Medicine; Liqin Zhao, Ph.D., University of Southern California

About the Author

Natalie L. Rasgon, M.D., Ph.D., is an associate professor in the departments of Psychiatry and Behavioral Sciences and Obstetrics and Gynecology at the Stanford University School of Medicine, where she is director for the Behavioral Neuroendocrinology and the Women's Wellness Programs.

Reviews

"Effectively and skillfully integrates current basic and clinical research data related to the use of HT and provides guidelines for treatment and future research."

- April L. Carbone - PsycCRITIQUES

"The Effects of Estrogen on Brain Function... is a nice collection of reviews from established experts in the estrogen field. These chapters provide a range of information from different levels of analysis that help to synthesize what is known about estrogen and the brain."

- Julie A. Dumas - Sex Roles

Endorsements

"An important contribution to the field, this volume combines the work of an excellent group of scholars, each an authority on the effects of estrogen."

- Jay Schulkin, The American College of Obstetricians and Gynecologists

"With women living longer today than ever before, the decision to initiate or continue hormone treatment can have an important impact on their quality of life and health status. The Effects of Estrogen on Brain Function provides a comprehensive update on recent research findings and is an indispensable guide to clinicians and scientists dealing with these issues. Dr. Rasgon has done a remarkable job in compiling an informative and well-written volume that includes some of the world’s leading experts in the field."

- Gary Small, M.D., Director, UCLA Center on Aging, Parlow-Solomon Professor on Aging, Professor of Psychiatry and Biobehavioral Sciences
Johns Hopkins University Press
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