Paperback / softback
December 7, 2021
9781421442747
English
152
32475
1
7.00 Inches (US)
5.00 Inches (US)
0.38 Inches (US)
$16.95 USD, £12.50 GBP
v2.1 Reference
Electronic book text
December 7, 2021
9781421442754
9781421442747
English
152
32475
1
7.00 Inches (US)
5.00 Inches (US)
$16.95 USD, £12.50 GBP
v2.1 Reference

Is Cancer Inevitable?

How can new understandings about cancer cell interactions help doctors better control, and eventually cure, cancer?

Cancer is a formidable enemy. In fact, people born in America since 1960 face a one in two chance of being diagnosed with cancer in their lifetimes. However, there's growing evidence that fewer cancers will be death sentences for patients. New approaches and understandings are transforming the medical world, increasing success rates for remissions, disease management, and cures. Dr. Ashani Weeraratna is at the forefront of this new level of care.

In Is Cancer Inevitable?, Weeraratna—a pioneering melanoma researcher whose work explores the role aging plays in cancer cells' spread and drug resistance—gives readers an inside look at several of the latest cancer advances. Detailing the actions that are reducing the disease's impact and exploring what the future may hold, she explains how the molecular mechanisms involved in metastasis and the cells' microenvironments influence cancer's development and progression. Over the years, she writes, our understanding of how cancer cells move throughout the body, change as they plant themselves in the body's microenvironments, and even communicate with one another have led to major insights about how cancer works. With compelling detail, she takes us inside her lab, revealing how new insights are leading to major breakthroughs, even among patients with Stage IV cancer. She also explains how age-related changes in the microenvironment contribute to multiple aspects of melanoma formation and development. Such scholarship, she argues, is moving us toward a day when more patients will be declared cancer-free.

An inspiring and deeply personal book, Is Cancer Inevitable? offers readers newfound hope.

Features
• Explores key insights and studies developed in recent years that have greatly influenced the world of cancer research, including how aging microenvironments within our bodies encourage metastasis and therapy resistance
• Guides readers through Dr. Ashani Weeraratna's personal story of coming to the United States from Lesotho at the age of 17 and rising to become one of the pioneers in her field
• Brings readers inside Weeraratna's lab, describing both the processes and the missions of her work
• Raises awareness about how cancer works within the body and what any patient or family encountering the disease needs to understand—while also offering them hope based on new and forthcoming diagnostic and treatment methods
• Outlines why we will never control—let alone cure—cancer if we don't find a common purpose and come together in collaboration, inviting the greatest minds from around the world to participate in finding and implementing solutions

Johns Hopkins Wavelengths

In classrooms, field stations, and laboratories in Baltimore and around the world, the Bloomberg Distinguished Professors of Johns Hopkins University are opening the boundaries of our understanding of many of the world's most complex challenges. The Johns Hopkins Wavelengths book series brings readers inside their stories, illustrating how their pioneering discoveries benefit people in their neighborhoods and across the globe in artificial intelligence, cancer research, food systems' environmental impacts, health equity, science diplomacy, and other critical arenas of study. Through these compelling narratives, their insights will spark conversations from dorm rooms to dining rooms to boardrooms.

About the Authors

Ashani T. Weeraratna is a Bloomberg Distinguished Professor of Cancer Biology and the chair of the Department of Biochemistry and Molecular Biology at the Johns Hopkins Bloomberg School of Public Health. A groundbreaking researcher focused on the connections between aging and cancer, Weeraratna is also the co-program leader of the Cancer Invasion and Metastasis Program at the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, and the president of the Society for Melanoma Research. A writer in residence at Johns Hopkins University, Tim Wendel is the author of 15 books, including Summer of '68: The Season That Changed Baseball—and America—Forever, Castro's Curveball, and Cancer Crossings: A Brother, His Doctors, and the Quest for a Cure to Childhood Leukemia. His work has appeared in the New York Times, the Washington Post, National Geographic, and elsewhere.

Endorsements

"This is storytelling at its best. The journey of the author's upbringing and how her experience with myriad cultures has informed Dr. Weeraratna's work in the pursuit of understanding and defeating cancer as we know it is fascinating. Her story is particularly inspiring for anyone who might be interested in pursuing a career in STEM."

- Sung Poblete, PhD, RN, CEO, Stand Up To Cancer

"Dr. Weeraratna's amalgam of her personal history, her lab's cutting-edge research on the increasingly important link between cancer and aging, and the promise, hopes, and limitations of future anti-cancer therapies is a beautifully accessible account for scientific and nonscientific audiences alike."

- Judith Campisi, PhD, Buck Institute for Research on Aging / Lawrence Berkeley National Laboratory

"This clear and optimistic insider's view on how cancers form and become aggressive, and what's being done to alter their courses toward remissions and recovery, is a captivating read for anyone whose life has been touched by the disease. Dr. Weeraratna—an acclaimed researcher on age-related differences in how people respond to certain cancer treatments as well as a fierce advocate for junior faculty, women, immigrants, and people of color in science—presents the human side of medical lab work and will inspire budding future scientists from underrepresented backgrounds and other countries."

- James DeGregori, MD, University of Colorado

"As Winston Churchill noted, 'The past no longer enables us even simply to measure the future.' This certainly describes the blinding pace of cancer research today, including Dr. Weeraratna's investigations at the vanguard of aging's impacts on metastases and treatments. This book is told through the eyes of a woman whose fighting spirit was sparked in her formative years in Sri Lanka and Lesotho. Her determination brought her to the United States as a college student and led her to prestigious positions at the National Institutes of Health, the Wistar Institute, Johns Hopkins University, and as a member on President Biden's National Cancer Advisory Board. The clear, fascinating narrative of both the nature of cancer and advancements in the campaigns against it provides us with evidence-informed hope from her own and others' labs that we're actually beginning to 'measure the future' of this horrible disease."

- Jeffrey Trent, MD, FACMGG, President/Research Director, Translational Genomics Research Institute (TGen)

"The intriguing complexities of cancer—how it develops into a deadly disease, its extraordinary resilience against treatment, its attacks on the immune system, and its interplay with aging—are unveiled before the reader's eyes while being immersed in Weeraratna's life stories. She takes us on a captivating journey through what shaped her as a person and as a scientist, revealing how each step in her career added a new piece to the puzzle of her research."

- Margaret Foti, Phd, MD, CEO, American Association for Cancer Research
Johns Hopkins University Press
Johns Hopkins Wavelengths
From 17

9781421442747 : is-cancer-inevitable-weeraratna-wendel
Paperback / softback
December 7, 2021
$16.95 USD
9781421442754 : is-cancer-inevitable-weeraratna-wendel
Electronic book text
December 7, 2021
$16.95 USD

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