Hardback
December 6, 2022
9781421444871
English
240
67753
9.00 Inches (US)
6.00 Inches (US)
0.88 Inches (US)
$28.00 USD, £20.50 GBP
v2.1 Reference
Electronic book text
December 6, 2022
9781421444888
9781421444871
English
240
67753
9.00 Inches (US)
6.00 Inches (US)
$28.00 USD, £20.50 GBP
v2.1 Reference

Building Breakthroughs

On the Frontier of Medical Innovation

From mRNA vaccines to gene therapies, the next frontier of medical innovation is here.

In Building Breakthroughs, Raju Prasad tells the story of important advancements in biotechnology and medical innovation from gene therapies to mRNA vaccines, providing historical context and examining cutting-edge research. Based on in-depth interviews with both the scientists who developed these discoveries and the patients who have benefitted from them, Building Breakthroughs reveals the key players behind drug development and the inner workings of this essential business.

Through stories of patients and their families, and of the researchers creating new treatments, Prasad reveals how cell therapies are advancing to treat childhood leukemia and a form of lymphoma, how a gene therapy was established to treat the rare disease spinal muscular atrophy type I, and potentially curative therapies that are being developed for sickle cell disease. By examining the clinical trial and regulatory paths each therapy took to reach approval, Prasad uncovers the building blocks of biotechnology innovation and the investments that must be made to catalyze the development of future breakthroughs. He also explores issues of scientific communication and misinformation, providing recommendations for improvements in the future.

For those seeking to understand the vitally important processes that lead to new medicines and the surrounding ecosystem that is enabling the next generation of innovative medicines that have the potential to transform patient outcomes, Building Breakthroughs is essential reading.

About the Author

Raju Prasad, PhD (CHICAGO, IL), is a partner and biotechnology analyst at William Blair, focusing on cell therapy, gene therapy, and gene editing. Dr. Prasad previously worked as a research associate with the University of North Carolina at Chapel Hill's Gillings School of Global Public Health and as an independent consultant with the US Environmental Protection Agency.

Endorsements

"Prasad has woven together a book that is rich in detail and brings to life compelling stories about both patients and the medicines that have helped them."

- Rohit Khanna, author of Misunderstanding Health: Making Sense of America's Broken Health Care System
Johns Hopkins University Press
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Hardback
December 6, 2022
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