Analysis of Human Genetic Linkage, third edition
The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book.
New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to linkage and association analysis. A chapter on two-locus inheritance introduces the reader to many of the intricate aspects of complex traits. Although the book's primary audience is in the field of genetics, physicians and others without sophisticated training in genetics can understand and apply the principles and techniques discussed.
About the Author
Jurg Ott is a professor and head of the Laboratory of Statistical Genetics at Rockefeller University. He is editor-in-chief of Human Heredity and the author of the first generally available computer program on human linkage analysis (LIPED).
"For the last decade this book has been the unrivaled standard text on human genetic linkage analysis."
"One of the best books that cover the theory behind linkage analysis. Scientists with an interest in genetic linkage analysis should definitely consider allocating space on their bookshelves for this book."
"A valuable resource. It is the most accessible work on the subject, and should be in the collection of everyone interested in mapping human genes."
Other Titles in MEDICAL / Genetics
Other Titles in Medical genetics